Analytical Data
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基因名
CALM1
- Application
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别名
CALM1；CALM；Calmodulin-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P0DP23
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表达区间
1-149aa
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氨基酸序列
MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQVNYE EFVQMMTAK
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CALM1 (Calmodulin 1) is an essential calcium-binding protein that plays a crucial role in various cellular processes, including muscle contraction, neurotransmitter release, and gene expression regulation. The CALM1 gene encodes a protein that interacts with numerous target proteins in response to changes in intracellular calcium levels, acting as a mediator for calcium signaling pathways. Dysregulation of CALM1 has been implicated in various diseases, including cardiovascular disorders, neurological conditions, and cancer. Recent advances in recombinant protein technology have enabled researchers to produce CALM1 at significant scales, facilitating extensive studies to elucidate its structure, function, and interactions with other proteins. Understanding the detailed mechanisms by which CALM1 operates and its role in pathology could provide valuable insights for developing novel therapeutic approaches aimed at modulating calcium signaling pathways. Moreover, recombinant CALM1 can serve as a tool for biochemical assays and structural studies, contributing to a deeper understanding of calcium-dependent signaling processes in health and disease. This research not only enhances our knowledge of CALM1’s biological significance but also opens avenues for innovative treatments targeting calcium dysregulation in various pathological contexts.
