Analytical Data
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Gene name
BTBD14A
- Application
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Alternative Names
Nucleus accumbens-associated Protein 2. NAC-2. BTB/POZ domain-containing Protein 14A
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96BF6
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Expression Region
1-587aa
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AA Sequence
MSQMLHIEIPNFGNTVLGCLNEQRLLGLYCDVSIVVKGQAFKAHRAVLAASSLYFRDLFSGNSKSAFELPGSVPPACFQQILSFCYTGRLTMTASEQLVVMYTAGFLQIQHIVERGTDLMFKVSSPHCDSQTAVIEDAGSEPQSPCNQLQPAAAAAAPYVVSPSVPIPLLTRVKHEAMELPPAGPGLAPKRPLETGPRDGVAVAAGAAVAAGTAPLKLPRVSYYGVPSLATLIPGIQQMPYPQGERTSPGASSLPTTDSPTSYHNEEDEEDDEAYDTMVEEQYGQMYIKASGSYAVQEKPEPVPLESRSCVLIRRDLVALPASLISQIGYRCHPKLYSEGDPGEKLELVAGSGVYITRGQLMNCHLCAGVKHKVLLRRLLATFFDRNTLANSCGTGIRSSTSDPSRKPLDSRVLNAVKLYCQNFAPSFKESEMNVIAADMCTNARRVRKRWLPKIKSMLPEGVEMYRTVMGSAAASVPLDPEFPPAAAQVFEQRIYAERRGDAATIVALRTDAVNVDLSAAANPAFDAGEEVDGAGSVIQEVAAPEPLPADGQSPPQPFEQGGGGPSRPQTPAAAARRPEGTYAGTL
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Molecular Weight
89.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BTBD14A, part of the BTB-Kelch protein family, has garnered attention for its potential role in mediating various cellular processes, particularly in the regulation of protein interactions and cellular signaling pathways. Recent studies suggest that BTBD14A may be involved in modulating the immune response and influencing cancer progression, making it a target of interest for therapeutic intervention. The protein's unique structural features, including its BTB (Broad-Complex, Tramtrack, and Bric-a-brac) and Kelch domains, enable it to interact with multiple partner proteins, serving as an important mediator in signaling cascades. Research into the recombinant expression of BTBD14A aims to elucidate its functional roles further and facilitate the development of targeted therapies, particularly in oncology and immunology. Understanding the biochemical mechanisms underpinning BTBD14A's functions may provide insights into its contributions to disease pathways, thereby enhancing our knowledge of potential intervention strategies. As such, the study of BTBD14A not only contributes to the broader understanding of cellular regulatory mechanisms but also holds promise for advancing therapeutic approaches in diseases linked to its dysregulation.
