Analytical Data
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Gene name
BCAS4
- Application
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Alternative Names
BCAS4Breast carcinoma-amplified sequence 4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TDM0
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Expression Region
1-211aa
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AA Sequence
MQRTGGGAPR PGRNHGLPGS LRQPDPVALL MLLVDADQPE PMRSGARELA LFLTPEPGAE AKEVEETIEG MLLRLEEFCS LADLIRSDTS QILEENIPVL KAKLTEMRGI YAKVDRLEAF VKMVGHHVAF LEADVLQAER DHGAFPQALR RWLGSAGLPS FRNVECSGTI PARCNLRLPG SSDSPASASQ VAGITEVTCT GARDVRAAHT V
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Molecular Weight
22.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BCAS4 (Breast Cancer Amplified Sequence 4) is a protein that has garnered significant attention in cancer research due to its overexpression in various malignancies, particularly breast cancer. Its role in tumorigenesis is thought to involve functions related to cell proliferation, survival, and metastasis, making it a potential biomarker for aggressive cancer types. Studies suggest that BCAS4 may be linked to poor patient prognosis, thus highlighting its importance in understanding the molecular mechanisms underlying cancer progression. The importance of BCAS4 is further underscored by its association with the epithelial-to-mesenchymal transition (EMT), a process critical for cancer metastasis. As a result, scientists have focused on generating recombinant BCAS4 proteins to study their functional properties and interactions in cellular pathways. These recombinant proteins can be utilized in various assays, including immunological studies, structural analysis, and potential therapeutic applications. In summary, the investigation of BCAS4 through recombinant protein technology is pivotal for elucidating its biological roles in cancer and could lead to the development of novel diagnostic and therapeutic strategies.
