Analytical Data
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Gene name
PABPC1L2A
- Application
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Alternative Names
PABPC1L2; PABPC1L2A; PABPC1L2B; PAP1M_HUMAN; Poly(A) binding protein. cytoplasmic 1 like 2A; Polyadenylate binding protein 1 like 2; Polyadenylate-binding protein 1-like 2; RBM32A; RBM32B; RNA binding motif protein 32; RNA binding protein 32; RNA-binding motif protein 32; RNA-binding protein 32; RP11-493K23.3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5JQF8
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Expression Region
1-200 aa
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AA Sequence
MASLYVGDLH PEVTEAMLYE KFSPAGPILS IRICRDKITR RSLGYAYVNY QQPVDAKRAL ETLNFDVIKG RPVRIMWSQR DPSLRKSGVG NVFIKNLGKT IDNKALYNIF SAFGNILSCK VACDEKGPKG YGFVHFQKQE SAERAIDVMN GMFLNYRKIF VGRFKSHKER EAERGAWARQ STSADVKDFE EDTDEEATLR
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Molecular Weight
22.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PABPC1L2A, a member of the poly(A)-binding protein family, is known for its essential roles in mRNA metabolism, including mRNA stability, translation, and regulation. As a homolog of the main poly(A)-binding protein PABPC1, PABPC1L2A exhibits unique structural and functional characteristics that contribute to its specific role in gene expression regulation. Research on PABPC1L2A has been spurred by its potential implications in various biological processes and diseases. Studies suggest that it may play a significant role in the response to cellular stress, influencing the translation of selective mRNAs that are crucial for cell survival and adaptation. Additionally, aberrations in PABPC1L2A expression have been linked to several pathological conditions, including cancer, making it a target of interest for therapeutic strategies. The production of recombinant PABPC1L2A protein allows for detailed functional studies, enabling scientists to dissect its mechanisms of action at the molecular level. By investigating the interactions and interactions of PABPC1L2A with other cellular components, researchers aim to uncover its contribution to post-transcriptional regulation and its potential as a biomarker or therapeutic target in related diseases. Overall, the exploration of PABPC1L2A and its recombinant protein forms represents a promising avenue for understanding the complexities of gene regulation and its implications in health and disease.
