Analytical Data
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基因名
OXCT2
- Application
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别名
OXCT2; FKSG25; Succinyl-CoA:3-ketoacid coenzyme A transferase 2; mitochondrial; EC 2.8.3.5; 3-oxoacid CoA-transferase 2A; Testis-specific succinyl-CoA:3-oxoacid CoA-transferase; SCOT-t
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BYC2
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表达区间
40-517 aa
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氨基酸序列
A KFYADPVEMV KDISDGATVM IGGFGLCGIP ENLIAALLRT RVKDLQVVSS NVGVEDFGLG LLLAARQVRR IVCSYVGENT LCESQYLAGE LELELTPQGT LAERIRAGGA GVPAFYTPTG YGTLVQEGGA PIRYTPDGHL ALMSQPREVR EFNGDHFLLE RAIRADFALV KGWKADRAGN VVFRRSARNF NVPMCKAADV TAVEVEEIVE VGAFPPEDIH VPNIYVDRVI KGQKYEKRIE RLTILKEEDG DAGKEEDART RIIRRAALEF EDGMYANLGI GIPLLASNFI SPSMTVHLHS ENGILGLGPF PTEDEVDADL INAGKQTVTV LPGGCFFASD DSFAMIRGGH IQLTMLGAMQ VSKYGDLANW MIPGKKVKGM GGAMDLVSSQ KTRVVVTMQH CTKDNTPKIM EKCTMPLTGK RCVDRIITEK AVFDVHRKKE LTLRELWEGL TVDDIKKSTG CAFAVSPNLR PMQQVAP
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分子量
56.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OXCT2, or Oxidative Short-Chain Fatty Acid Transporter 2, is a crucial protein involved in the transport of short-chain fatty acids (SCFAs) across cellular membranes, playing a significant role in metabolic processes. Recent studies have highlighted the importance of OXCT2 in maintaining energy homeostasis and its potential link to various metabolic disorders, including obesity and diabetes. The protein is predominantly expressed in tissues such as the intestine, kidney, and brain, suggesting its pivotal role in nutrient absorption and metabolic signaling. Researchers are particularly interested in the mechanisms underlying OXCT2's function and regulation, as SCFAs have been shown to influence gut health, systemic inflammation, and overall metabolic health. Additionally, the role of OXCT2 in the gut-brain axis and its implications in neurodegenerative diseases is an emerging area of investigation. Understanding the structure, function, and regulation of OXCT2 can provide insights into its therapeutic potential and could lead to novel strategies for treating metabolic disorders linked to dysregulated SCFA transport. Given the increasing prevalence of metabolic diseases worldwide, elucidating the functional dynamics of OXCT2 is vital for developing targeted interventions aimed at improving metabolic health and function.
