Analytical Data
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Gene name
APOL6
- Application
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Alternative Names
MDNQAERESE AGVGLQRDED DAPLCEDVEL QDGDLSPEEK IFLREFPRLK EDLKGNIDKL RALADDIDKT HKKFTKANMV ATSTAVISGV MSLLGLALAP ATGGGSLLLS TAGQGLATAA GVTSIVSGTL ERSKNKEAQA RAEDILPTYD QEDREDEEEK ADYVTAAGKI IYNLRNTLKY AKKNVRAFWK LRANPRLANA TKRLLTTGQV SSRSRVQVQK AFAGTTLAMT KNARVLGGVM SAFSLGYDLA TLSKEWKHLK EGARTKFAEE LRAKALELER KLTELTQLYK SLQQKVRSRA RGVGKDLTGT CETEAYWKEL REHVWMWLWL CVCLCVCVYV QFT
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BWW8
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Expression Region
1-343aa
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AA Sequence
MDNQAERESE AGVGLQRDED DAPLCEDVEL QDGDLSPEEK IFLREFPRLK EDLKGNIDKL RALADDIDKT HKKFTKANMV ATSTAVISGV MSLLGLALAP ATGGGSLLLS TAGQGLATAA GVTSIVSGTL ERSKNKEAQA RAEDILPTYD QEDREDEEEK ADYVTAAGKI IYNLRNTLKY AKKNVRAFWK LRANPRLANA TKRLLTTGQV SSRSRVQVQK AFAGTTLAMT KNARVLGGVM SAFSLGYDLA TLSKEWKHLK EGARTKFAEE LRAKALELER KLTELTQLYK SLQQKVRSRA RGVGKDLTGT CETEAYWKEL REHVWMWLWL CVCLCVCVYV QFT
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Molecular Weight
38 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of APOL6, a member of the apolipoprotein L (APOL) family, has gained significance due to its potential roles in various biological processes and its implications in health and disease. APOL6, known for its involvement in lipid metabolism and immune response, is particularly intriguing because of its association with inflammatory conditions and metabolic disorders. Recent research has indicated that APOL6 may play a critical role in the regulation of cholesterol homeostasis and the modulation of inflammatory responses, highlighting its potential as a therapeutic target. Furthermore, mutations and dysregulation of APOL family members have been linked to diseases such as kidney disorders and cardiovascular diseases, making understanding APOL6 function and its mechanisms vital for developing novel therapeutic strategies. Ongoing studies aim to elucidate the biochemical properties of APOL6 through the expression and characterization of recombinant protein, which can provide insights into its structure-function relationships and interactions with other biomolecules. The findings from these investigations may not only enhance our understanding of APOL6 but also pave the way for innovative interventions in diseases where dysregulation of lipid metabolism and inflammation are prominent.
