Analytical Data
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Gene name
TINAGL1
- Application
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Alternative Names
TINAGL1；GIS5；Tubulointerstitial nephritis antigen-like
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9GZM7
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Expression Region
22-467aa
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AA Sequence
AQQGRGRRELAPGLHLRGIRDAGGRYCQEQDLCCRGRADDCALPYLGAIC YCDLFCNRTVSDCCPDFWDFCLGVPPPFPPIQGCMHGGRIYPVLGTYWDN CNRCTCQENRQWQCDQEPCLVDPDMIKAINQGNYGWQAGNHSAFWGMTLD EGIRYRLGTIRPSSSVMNMHEIYTVLNPGEVLPTAFEASEKWPNLIHEPL DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQQQGCR GGRLDGAWWFLRRRGVVSDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKR QATAHCPNSYVNNNDIYQVTPVYRLGSNDKEIMKELMENGPVQALMEVHE DFFLYKGGIYSHTPVSLGRPERYRRHGTHSVKITGWGEETLPDGRTLKYW TAANSWGPAWGERGHFRIVRGVNECDIESFVLGVWGRVGMEDMGHHVDHH HHHH
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Molecular Weight
51 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TINAGL1 (Tubulointerstitial Nephritis Antigen-Like 1) is a protein that has garnered interest in the field of biomedical research due to its potential role in various physiological and pathological processes. Initially identified for its involvement in kidney health, TINAGL1 has been implicated in immunological responses, particularly in the context of autoimmune diseases such as tubulointerstitial nephritis. Recent studies suggest that TINAGL1 may play a critical role in tissue repair and regeneration, hinting at its significance in managing chronic kidney conditions and associated complications. Furthermore, emerging research points to its potential as a biomarker for kidney disorders, which could enhance diagnostic and therapeutic strategies in clinical settings. The study of recombinant TINAGL1 protein offers an opportunity to elucidate its structural and functional properties, paving the way for deeper understanding of its mechanisms of action and interactions with other molecular pathways. This research has important implications not only for nephrology but also for broader applications in regenerative medicine and immunotherapy, highlighting the need for detailed investigations into TINAGL1's biological functions and therapeutic potential.
