Cat: PA2000-5492

Recombinant Human ANKRD21 Protein,His

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Analytical Data

  • Gene name

    ANKRD21

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    POTED; A26B3; ANKRD21; POTE; POTE ankyrin domain family member D; ANKRD26-like family B member 3

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q86YR6

  • Expression Region

    1-584aa

  • AA Sequence

    MVAEVCSMPT ASTVKKPFDL RSKMGKWCHH RFPCCRGSGK SNMGTSGDHD DSFMKMLRSK MGKCCRHCFP CCRGSGTSNV GTSGDHENSF MKMLRSKMGK WCCHCFPCCR GSGKSNVGAW GDYDHSAFME PRYHIRREDL DKLHRAAWWG KVPRKDLIVM LRDTDMNKRD KEKRTALHLA SANGNSEVVQ LLLDRRCQLN VLDNKKRTAL IKAIQCQEDE CVLMLLEHGA DRNIPDEYGN TALHYAIYNE DKLMAKALLL YGADIESKNK CGLTPLLLGV HEQKQQVVKF LIKKKANLNV LDRYGRTALI LAVCCGSASI VNLLLEQNVD VSSQDLSGQT AREYAVSSHH HVICELLSDY KEKQMLKISS ENSNPEQDLK LTSEEESQRL KVSENSQPEK MSQEPEINKD CDREVEEEIK KHGSNPVGLP ENLTNGASAG NGDDGLIPQR RSRKPENQQF PDTENEEYHS DEQNDTRKQL SEEQNTGISQ DEILTNKQKQ IEVAEQKMNS ELSLSHKKEE DLLRENSVLQ EEIAMLRLEL DETKHQNQLR ENKILEEIES VKEKTDKLLR AMQLNEEALT KTNI

  • Molecular Weight

    66.3 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

ANKRD21 is a protein that has garnered significant attention due to its role in cellular processes and potential implications in various diseases. As a member of the ankyrin repeat-containing protein family, ANKRD21 is implicated in diverse biological functions, including cell signaling, transcription regulation, and protein-protein interactions. Its structural characteristics, specifically the presence of ankyrin repeats, suggest a capacity for mediating complex interactions with other proteins, which could be essential for maintaining cellular homeostasis. Recent studies have highlighted the importance of ANKRD21 in specific developmental pathways and its potential involvement in the pathogenesis of diseases such as cancer and neurodegenerative disorders. The recombinant expression of ANKRD21 provides researchers with a powerful tool to dissect its functions and interactions in vitro, allowing for a greater understanding of its biological roles. By producing this protein in a recombinant form, scientists can overcome challenges related to its natural expression, enabling detailed biochemical assays and structural analyses. Furthermore, the study of ANKRD21 may lead to the identification of novel therapeutic targets or biomarkers, contributing to the development of new strategies in disease treatment and prevention. Therefore, ongoing research into the recombinant protein ANKRD21 holds promise for uncovering its mechanisms of action and therapeutic potential, fostering greater insight into the intricate networks regulating cellular function and disease pathways.

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