Analytical Data
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基因名
CD43
- Application
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别名
SPN;CD43;Leukosialin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P16150
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表达区间
20-253aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSSTTAVQT PTSGEPLVST SEPLSSKMYT TSITSDPKAD STGDQTSALP PSTSINEGSP LWTSIGASTG SPLPEPTTYQ EVSIKMSSVP QETPHATSHP AVPITANSLG SHTVTGGTIT TNSPETSSRT SGAPVTTAAS SLETSRGTSG PPLTMATVSL ETSKGTSGPP VTMATDSLET STGTTGPPVT MTTGSLEPSS GASGPQVSSV KLSTMMSPTT STNASTVPFR NPDENSR
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CD43, also known as leukosialin or sialophorin, is a cell surface glycoprotein predominantly expressed on leukocytes and plays a critical role in cell adhesion, signaling, and immune response modulation. The investigation of CD43 recombinant proteins has gained momentum due to its potential implications in various immunological disorders, cancer, and infectious diseases. Structurally, CD43 is characterized by its extensive extracellular domain, which is heavily glycosylated, imparting a complex and dynamic nature that impacts its function. Research efforts have focused on generating recombinant CD43 proteins to elucidate its biological roles and interactions with other immune cell receptors. Such recombinant proteins facilitate the exploration of CD43's involvement in cell-mediated immunity, lymphocyte activation, and the modulation of inflammatory responses. Moreover, understanding the structure-function relationship of CD43 through recombinant studies can aid in designing therapeutic strategies aimed at manipulating immune pathways for clinical benefit. The development of CD43-based biologics and therapeutic antibodies also presents novel avenues for targeting immune evasion mechanisms in tumors. Overall, the study of CD43 recombinant proteins represents a promising frontier in immunology and therapeutic development, highlighting the importance of this glycoprotein in human health and disease.
