Analytical Data
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基因名
OGFRL1
- Application
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别名
OGFRL1; Opioid growth factor receptor-like protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TC84
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表达区间
1-451 aa
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氨基酸序列
MGNLLGGVSF REPTTVEDCD STWQTDSEPE PEEPGPGGGS EGPGQESEQP AQPPEQAGGR PGASPAPDED AEAAGAEQGG DSTEATAKPK RSFYAARDLY KYRHQYPNFK DIRYQNDLSN LRFYKNKIPF KPDGVYIEEV LSKWKGDYEK LEHNHTYIQW LFPLREQGLN FYAKELTTYE IEEFKKTKEA IRRFLLAYKM MLEFFGIKLT DKTGNVARAV NWQERFQHLN ESQHNYLRIT RILKSLGELG YESFKSPLVK FILHEALVEN TIPNIKQSAL EYFVYTIRDR RERRKLLRFA QKHYTPSENF IWGPPRKEQS EGSKAQKMSS PLASSHNSQT SMHKKAKDSK NSSSAVHLNS KTAEDKKVAP KEPVEETDRP SPEPSNEAAK PRNTEKDSNA ENMNSQPEKT VTTPTEKKES VSPENNEEGG NDNQDNENPG NTNCHDVVLV Q
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分子量
51.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
OGFRL1, or Opioid Growth Factor Receptor-Like 1, is a receptor that has garnered significant attention in recent years due to its potential implications in various biological processes, particularly in cancer biology and neurobiology. Research suggests that OGFRL1 may play a role in modulating cellular responses to opioid growth factor (OGF), which is involved in regulating cell proliferation and survival. The interest in OGFRL1 is further heightened by its involvement in potential therapeutic applications, such as targeted cancer therapies and pain management. Previous studies have indicated that OGFRL1 can influence tumor cell behaviors, including migration and invasion, thereby suggesting its importance in the metastasis of various cancers. Additionally, the receptor's expression patterns have been observed in different tissues, indicating a broader potential role in physiological and pathological conditions. The recombinant expression of OGFRL1 protein is essential for elucidating its structure-function relationships and interactions with ligands. Understanding the functional dynamics of OGFRL1 may uncover novel insights into its mechanisms and pave the way for innovative treatment strategies against cancers and other diseases where opioid pathways are dysregulated.
