Analytical Data
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Gene name
AHCYL1
- Application
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Alternative Names
AHCYL1；INSP3R1；Inositol 1.4.5-trisphosphate-gated calcium channel ITPR1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43865
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Expression Region
2-530aa
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AA Sequence
SMPDAMPLP GVGEELKQAK EIEDAEKYSF MATVTKAPKK QIQFADDMQE FTKFPTKTGR RSLSRSISQS STDSYSSAAS YTDSSDDEVS PREKQQTNSK GSSNFCVKNI KQAEFGRREI EIAEQDMSAL ISLRKRAQGE KPLAGAKIVG CTHITAQTAV LIETLCALGA QCRWSACNIY STQNEVAAAL AEAGVAVFAW KGESEDDFWW CIDRCVNMDG WQANMILDDG GDLTHWVYKK YPNVFKKIRG IVEESVTGVH RLYQLSKAGK LCVPAMNVND SVTKQKFDNL YCCRESILDG LKRTTDVMFG GKQVVVCGYG EVGKGCCAAL KALGAIVYIT EIDPICALQA CMDGFRVVKL NEVIRQVDVV ITCTGNKNVV TREHLDRMKN SCIVCNMGHS NTEIDVTSLR TPELTWERVR SQVDHVIWPD GKRVVLLAEG RLLNLSCSTV PTFVLSITAT TQALALIELY NAPEGRYKQD VYLLPKKMDE YVASLHLPSF DAHLTELTDD QAKYLGLNKN GPFKPNYYRY
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Molecular Weight
58.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
AHCYL1, or S-adenosylhomocysteine hydrolase-like 1, is a protein that has garnered attention in the field of molecular biology due to its potential roles in cellular processes and disease mechanisms. As a member of the S-adenosylhomocysteine hydrolase family, AHCYL1 is implicated in the regulation of cellular methylation processes, which are critical for numerous biological functions, including DNA methylation, gene expression regulation, and neurotransmitter synthesis. Recent studies have indicated that altered expression levels of AHCYL1 may be associated with various pathological conditions, including cancer and neurological disorders, thereby making it a significant focus for therapeutic research. The recombinant expression of AHCYL1 is crucial for understanding its functional characteristics, interacting partners, and the downstream effects of its activity. By producing AHCYL1 in a recombinant system, researchers can study its enzymatic mechanisms, assess its structural properties, and explore its role in cellular signaling pathways. This research could provide insights into the enzyme's potential as a biomarker for disease and its utility as a target for drug development, ultimately contributing to our understanding of metabolism and disease.
