Analytical Data
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基因名
SCG5
- Application
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别名
SCG5;SGNE1;Neuroendocrine Protein 7B2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P05408
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表达区间
27-212aa
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氨基酸序列
MYSPRTPDRV SEADIQRLLH GVMEQLGIAR PRVEYPAHQA MNLVGPQSIE GGAHEGLQHL GPFGNIPNIV AELTGDNIPK DFSEDQGYPD PPNPCPVGKT ADDGCLENTP DTAEFSREFQ LHQHLSDPEH DYPGLGKWNK KLLYEKMKGG ERRKRRSVNP YLQGQRLDNV VAKKSVPHFS DEDKDPE LEH HHHHH
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SCG5 (secretogranin V) is a member of the granin family of proteins, predominantly expressed in neuroendocrine cells and involved in the storage and release of neuropeptides and catecholamines. As a proprotein, SCG5 plays a crucial role in regulating synaptic transmission and neuroendocrine signaling. Abnormal expression or dysfunction of SCG5 has been implicated in various neurological disorders and diseases, including schizophrenia and depression, making it a significant target for therapeutic intervention. Researchers have focused on the recombinant production of SCG5 to better understand its structure, function, and interactions within neuroendocrine systems. Recombination technology facilitates large-scale production of SCG5 for biochemical studies and potential drug development, which can provide insights into its role in neuroendocrine pathways and its potential as a biomarker or therapeutic target. Additionally, characterizing SCG5 at a molecular level may unveil novel mechanisms of neuroendocrine regulation, contributing to the development of targeted therapies for related disorders. The study of SCG5 recombinant protein not only enhances our understanding of neuroendocrine function but also presents opportunities for advancing strategies in treating neuropsychiatric illnesses.
