Analytical Data
-
Gene name
SCG5
- Application
-
Alternative Names
SCG5;SGNE1;Neuroendocrine Protein 7B2
-
Species
Human
-
Source
E. coli
-
Tag
His tag N-Terminus
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
P05408
-
Expression Region
27-212aa
-
AA Sequence
MYSPRTPDRV SEADIQRLLH GVMEQLGIAR PRVEYPAHQA MNLVGPQSIE GGAHEGLQHL GPFGNIPNIV AELTGDNIPK DFSEDQGYPD PPNPCPVGKT ADDGCLENTP DTAEFSREFQ LHQHLSDPEH DYPGLGKWNK KLLYEKMKGG ERRKRRSVNP YLQGQRLDNV VAKKSVPHFS DEDKDPE LEH HHHHH
-
Molecular Weight
22 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SCG5 (secretogranin V) is a member of the granin family of proteins, predominantly expressed in neuroendocrine cells and involved in the storage and release of neuropeptides and catecholamines. As a proprotein, SCG5 plays a crucial role in regulating synaptic transmission and neuroendocrine signaling. Abnormal expression or dysfunction of SCG5 has been implicated in various neurological disorders and diseases, including schizophrenia and depression, making it a significant target for therapeutic intervention. Researchers have focused on the recombinant production of SCG5 to better understand its structure, function, and interactions within neuroendocrine systems. Recombination technology facilitates large-scale production of SCG5 for biochemical studies and potential drug development, which can provide insights into its role in neuroendocrine pathways and its potential as a biomarker or therapeutic target. Additionally, characterizing SCG5 at a molecular level may unveil novel mechanisms of neuroendocrine regulation, contributing to the development of targeted therapies for related disorders. The study of SCG5 recombinant protein not only enhances our understanding of neuroendocrine function but also presents opportunities for advancing strategies in treating neuropsychiatric illnesses.
