Cat: PA1000-2800

Recombinant Human RWDD1 Protein,His

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Analytical Data

  • Gene name

    RWDD1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RWDD1;DFRP2;RWD domain-containing Protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9H446

  • Expression Region

    1-243aa

  • AA Sequence

    MGSSHHHHHHSSGLVPRGSHMGSMTDYGEEQRNELEALESIYPDSFTVLS ENPPSFTITVTSEAGENDETVQTTLKFTYSEKYPDEAPLYEIFSQENLED NDVSDILKLLALQAEENLGMVMIFTLVTAVQEKLNEIVDQIKTRREEEKK QKEKEAEEAEKQLFHGTPVTIENFLNWKAKFDAELLEIKKKRMKEEEQAG KNKLSGKQLFETDHNLDTSDIQFLEDAGNNVEVDESLFQEMDDLELEDDE DDPDYNPADPESDSAD

  • Molecular Weight

    30 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RWDD1 (Regulator of Wnt Signaling Pathway Domain Containing 1) is a protein that has garnered attention due to its potential role in various cellular processes, particularly in the regulation of the Wnt signaling pathway, which is crucial for cell proliferation, differentiation, and development. Research indicates that RWDD1 may be involved in cellular responses to environmental stimuli and stress, suggesting a multifunctional role in maintaining cellular homeostasis. It has been implicated in several physiological and pathological conditions, including cancer, where dysregulation of Wnt signaling is a common feature. Studies have shown that RWDD1 can interact with various signaling molecules, affecting cellular outcomes and influencing tumor progression. Furthermore, understanding the molecular mechanisms underlying the action of RWDD1 could provide insights into novel therapeutic strategies targeting Wnt-related disorders. As a result, RWDD1 has emerged as a significant subject of interest in biomedical research, prompting investigations into its structure, function, and potential applications in disease treatment. Ongoing research aims to elucidate the precise roles of RWDD1 in cellular signaling pathways and its impact on health and disease, paving the way for advancements in targeted therapies and novel drug development.

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