Cat: PA1000-2784

Recombinant Human RPS4X Protein,His

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Analytical Data

  • Gene name

    RPS4X

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    RPS4X;CCG2;RPS4;SCAR;Small ribosomal subunit Protein eS4. X isoform

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P62701

  • Expression Region

    2-263aa

  • AA Sequence

    ARGPKKHLK RVAAPKHWML DKLTGVFAPR PSTGPHKLRE CLPLIIFLRN RLKYALTGDE VKKICMQRFI KIDGKVRTDI TYPAGFMDVI SIDKTGENFR LIYDTKGRFA VHRITPEEAK YKLCKVRKIF VGTKGIPHLV THDARTIRYP DPLIKVNDTI QIDLETGKIT DFIKFDTGNL CMVTGGANLG RIGVITNRER HPGSFDVVHV KDANGNSFAT RLSNIFVIGK GNKPWISLPR GKGIRLTIAE ERDKRLAAKQ SSG

  • Molecular Weight

    32 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RPS4X, or Ribosomal Protein S4, X-Linked, is a crucial component of the ribosomal machinery, playing a significant role in protein synthesis. It is encoded by the RPS4X gene located on the X chromosome and is vital for the assembly of ribosomes, which are essential for translating mRNA into proteins. Research into RPS4X has gained attention due to its involvement in various cellular processes and its potential implications in diseases. Mutations or dysregulation of this protein have been linked to specific disorders, including Diamond-Blackfan anemia, a type of blood disorder characterized by the failure of bone marrow to produce sufficient red blood cells. Furthermore, given its X-linked inheritance pattern, alterations in RPS4X can differ between sexes, contributing to an understanding of sex-linked diseases. Studies have utilized recombinant DNA technology to express and purify RPS4X protein in suitable systems, enabling detailed investigations into its structural and functional properties. These studies are critical for elucidating the role of RPS4X in cellular mechanisms and could provide insights into therapeutic approaches for associated medical conditions. Understanding RPS4X's function not only enhances our knowledge of ribosome biology but also provides a framework for exploring the genetic underpinnings of related human diseases.

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