Analytical Data
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Gene name
MFSD2
- Application
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Alternative Names
Sodium-dependent lysophosphatidylcholine symporter 1. NLS1. Sodium-dependent LPC symporter 1. Major facilitator superfamily domain-containing protein 2A. HsMFSD2A. MFSD2a
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NA29
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Expression Region
1-530 aa
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AA Sequence
MAKGEGAESGSAAGLLPTSILQSTERPAQVKKEPKKKKQQLSVCNKLCYALGGAPYQVTGCALGFFLQIYLLDVAQVGPFSASIILFVGRAWDAITDPLVGLCISKSPWTCLGRLMPWIIFSTPLAVIAYFLIWFVPDFPHGQTYWYLLFYCLFETMVTCFHVPYSALTMFISTEQTERDSATAYRMTVEVLGTVLGTAIQGQIVGQADTPCFQDLNSSTVASQSANHTHGTTSHRETQKAYLLAAGVIVCIYIICAVILILGVREQREPYEAQQSEPIAYFRGLRLVMSHGPYIKLITGFLFTSLAFMLVEGNFVLFCTYTLGFRNEFQNLLLAIMLSATLTIPIWQWFLTRFGKKTAVYVGISSAVPFLILVALMESNLIITYAVAVAAGISVAAAFLLPWSMLPDVIDDFHLKQPHFHGTEPIFFSFYVFFTKFASGVSLGISTLSLDFAGYQTRGCSQPERVKFTLNMLVTMAPIVLILLGLLLFKMYPIDEERRRQNKKALQALRDEASSSGCSETDSTELASIL
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Molecular Weight
85 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MFSD2 (Major Facilitator Superfamily Domain Containing 2) is a member of the major facilitator superfamily of transporters, which has gained considerable attention in research due to its potential roles in cellular transport mechanisms and its implications in various physiological processes. Initially identified as a transporter involved in the uptake of fatty acids and other essential nutrients, MFSD2 has been implicated in several health conditions, including obesity, metabolic disorders, and neurodegenerative diseases. Its expression patterns and functional significance in different tissues, particularly in the brain, highlight its importance in maintaining cellular homeostasis and energy balance. The study of recombinant MFSD2 protein has become essential for elucidating its structure-function relationships and understanding the molecular mechanisms of substrate binding and transport. By producing and characterizing MFSD2 as a recombinant protein, researchers can investigate its interactions with potential ligands, assess its transport capabilities, and explore its regulatory mechanisms. The insights gained from these studies may pave the way for the development of novel therapeutic strategies targeting MFSD2-related pathways, ultimately contributing to the treatment of diseases linked to dysfunctional nutrient transport. Thus, the research on MFSD2 and its recombinant protein holds significant promise in understanding both fundamental biological processes and the pathological changes associated with various health conditions.
