Analytical Data
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基因名
GNTI
- Application
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别名
GNTI；CGL1；Alpha-1.3-mannosyl-glycoProtein 2-beta-N-acetylglucosaminyltransferase
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9XGM8
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表达区间
25-444aa
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氨基酸序列
RLFQTQSQYADRLSSAIESENHCTSQMRGLIDEVSIKQSRIVALEDMKNRQDEELVQLKDLIQTFEKKGIAKLTQGGQMPVAAVVVMACSRADYLERTVKSVLTYQTPVASKYPLFISQDGSDQAVKSKSLSYNQLTYMQHLDFEPVVTERPGELTAYYKIARHYKWALDQLFYKHKFSRVIILEDDMEIAPDFFDYFEAAASLMDRDKTIMAASSWNDNGQKQFVHDPYALYRSDFFPGLGWMLKRSTWDELSPKWPKAYWDDWLRLKENHKGRQFIRPEVCRTYNFGEHGSSLGQFFSQYLEPIKLNDVTVDWKAKDLGYLTEGNYTKYFSGLVRQARPIQGSDLVLKAQNIKDDVRIRYKDQVEFERIAGEFGIFEEWKDGVPRTAYKGVVVFRIQTTRRVFLVGPDSVMQLGIRNS
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分子量
51.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GNTI, or Glycerol-3-phosphate acyltransferase, is an enzyme implicated in the regulation of lipid metabolism and synthesis in various biological systems. Research on GNTI has gained momentum due to its potential role in influencing cellular energy homeostasis and membrane dynamics. Disruptions in lipid metabolism are linked to several metabolic disorders, including obesity, diabetes, and cardiovascular diseases, underscoring the need for a deeper understanding of GNTI's functions and mechanisms. Moreover, GNTI is of interest in the field of biochemistry and molecular biology for its involvement in phospholipid biosynthesis pathways, which are crucial for cell membrane integrity and signaling. Investigating the structural and functional aspects of GNTI, particularly through recombinant protein studies, allows scientists to explore its catalytic mechanisms and regulatory mechanisms in detail. This research not only advances our understanding of fundamental biological processes but also opens avenues for developing therapeutic strategies targeting lipid-related disorders. Overall, the study of GNTI and its recombinant protein form is pivotal in bridging gaps in our current knowledge of lipid metabolism and its implications for human health.
