Analytical Data
-
基因名
PURA
- Application
-
别名
PURA；PUR1；Transcriptional activator Protein Pur-alpha
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q00577
-
表达区间
1-322aa
-
氨基酸序列
MADRDSGSEQ GGAALGSGGS LGHPGSGSGS GGGGGGGGGG GGSGGGGGGA PGGLQHETQE LASKRVDIQN KRFYLDVKQN AKGRFLKIAE VGAGGNKSRL TLSMSVAVEF RDYLGDFIEH YAQLGPSQPP DLAQAQDEPR RALKSEFLVR ENRKYYMDLK ENQRGRFLRI RQTVNRGPGL GSTQGQTIAL PAQGLIEFRD ALAKLIDDYG VEEEPAELPE GTSLTVDNKR FFFDVGSNKY GVFMRVSEVK PTYRNSITVP YKVWAKFGHT FCKYSEEMKK IQEKQREKRA ACEQLHQQQQ QQQEETAAAT LLLQGEEEGE ED
-
分子量
34.9 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PURA is a gene that encodes a protein known as purine-rich element binding protein A, which plays a pivotal role in the regulation of gene expression and cellular processes, particularly in the context of neural development and function. Recent studies have highlighted the significance of PURA in various neurological disorders, including intellectual disabilities and autism spectrum disorders, where mutations in the PURA gene can disrupt normal brain development and function. This has prompted extensive research into the molecular mechanisms by which PURA operates, particularly regarding its interactions with RNA and DNA elements that influence transcriptional regulation. Additionally, PURA is being explored for its potential as a therapeutic target due to its involvement in neural pathways that, when dysregulated, contribute to disease pathogenesis. As scientists delve deeper into the complexities of PURA's function, understanding its role in epigenetic regulation and gene networks becomes crucial for developing interventions that may ameliorate conditions associated with PURA mutations. Ultimately, unveiling the biological underpinnings of PURA not only enriches our knowledge of developmental neuroscience but also holds promise for innovative treatments for related disorders in the future.
