Analytical Data
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Gene name
LUC7L2
- Application
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Alternative Names
CGI 59; CGI 74; FLJ10657; hLuc7B2; LC7L2_HUMAN; LUC7 like 2 (S. cerevisiae) ; LUC7B2; LUC7L2; Putative RNA binding protein Luc7 like 2; Putative RNA-binding protein Luc7-like 2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y383
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Expression Region
1-391aa
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AA Sequence
MPAYLNLQGSVRKAPHSPSRDTTRQRIKFSDDRVCKSHLLNCCPHDVLSGTRMDLGECLKVHDLALRADYEIASKEQDFFFELDAMDHLQSFIADCDRRTEVAKKRLAETQEEISAEVAAKAERVHELNEEIGKLLAKVEQLGAEGNVEESQKVMDEVEKARAKKREAEEVYRNSMPASSFQQQKLRVCEVCSAYLGLHDNDRRLADHFGGKLHLGFIEIREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHRSRSMSRERKRRTRSKSREKRHRHRSRSSSRSRSRSHQRSRHSSRDRSRERSKRRSSKERFRDQDLASCDRDRSSRDRSPRDRDRKDKKRSYESANGRSEDRRSSEEREAGEI
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Molecular Weight
72.8 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LUC7L2 (LUC7-like protein 2) is a member of the Luc7 protein family, which plays a crucial role in pre-mRNA splicing and has been implicated in various cellular processes. Its significance in the regulation of gene expression and splicing dynamics is increasingly recognized, making it a focus of interest in molecular biology research. The reconstitution of LUC7L2 as a recombinant protein allows for the exploration of its functional properties, interactions with other splicing factors, and its role in the spliceosome assembly. Understanding the structure-function relationship of LUC7L2 could provide insights into the molecular mechanisms underlying splicing regulation and shed light on its potential involvement in diseases associated with splicing dysregulation, such as certain cancers and neurodegenerative disorders. Additionally, studying LUC7L2's interactions with RNA and other proteins can enhance our understanding of the complex network involved in gene expression and may open new avenues for therapeutic interventions targeting splicing mechanisms. Thus, the research on LUC7L2 recombinant protein not only contributes to fundamental biological knowledge but also holds translational potential in the context of human health and disease.
