Analytical Data
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Gene name
LRRC58
- Application
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Alternative Names
LRRC58; Leucine-rich repeat-containing protein 58
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96CX6
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Expression Region
1-371aa
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AA Sequence
MEEAGAAVVTAGEAELNWSRLSVSTETLESELEARGEERRGAREALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALPKGLAQSPLCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRNISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAARRMQKVLLG
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Molecular Weight
67.21 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
LRRC58, a member of the Leucine-Rich Repeat Containing protein family, has emerged as a significant focus of research due to its potential roles in cellular processes and disease mechanisms. Initially identified for its expression in various tissues, LRRC58 has been implicated in crucial biological functions, including immune response modulation and the regulation of signal transduction pathways. Recent studies suggest that LRRC58 may play a role in the development and functioning of the immune system, potentially influencing the behavior of immune cells such as T lymphocytes and macrophages. Additionally, aberrations in LRRC58 expression or function have been linked to various pathological conditions, including autoimmune diseases and certain cancers. Investigating the structural and functional aspects of LRRC58 through recombinant protein technologies has provided insights into its mechanisms of action and its protein-protein interactions. Understanding LRRC58 on a molecular level could pave the way for novel therapeutic approaches targeting immune-related disorders and malignant diseases, making it a promising candidate for further exploration in both basic and translational research contexts.
