Cat: PA1000-2094

Recombinant Human NCALD Protein,His

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Analytical Data

  • 基因名

    NCALD

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    NCALD;Neurocalcin-delta

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P61601

  • 表达区间

    1-193aa

  • 氨基酸序列

    MGSSHHHHHH SSGLVPRGSH MGKQNSKLRP EVMQDLLEST DFTEHEIQEW YKGFLRDCPS GHLSMEEFKK IYGNFFPYGD ASKFAEHVFR TFDANGDGTI DFREFIIALS VTSRGKLEQK LKWAFSMYDL DGNGYISKAE MLEIVQAIYK MVSSVMKMPE DESTPEKRTE KIFRQMDTNR DGKLSLEEFI RGAKSDPSIV RLLQCDPSSA GQF

  • 分子量

    24 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

NCALD, or Neuronal Calmodulin-Binding Protein, has garnered attention in the field of molecular neuroscience due to its unique role as a calmodulin-binding protein that is primarily expressed in the brain. Recent studies have highlighted its potential involvement in various cellular processes, including synaptic transmission, neuronal development, and calcium signaling. NCALD's interaction with calmodulin, a key calcium sensor, suggests that it may play a critical role in modulating calcium-dependent signaling pathways, which are essential for neurotransmitter release and synaptic plasticity. Research has indicated that dysregulation of NCALD expression may be linked to neurodegenerative diseases and psychiatric disorders, making it a potential biomarker for neurological conditions. The recombinant expression of NCALD protein in vitro provides an invaluable tool for further elucidating its functional mechanisms and interactions with other proteins. This is particularly important for understanding how alterations in NCALD activity can contribute to pathological processes in the nervous system. The ongoing study of NCALD not only aims to clarify its biological significance but also to explore its therapeutic potential in treating neurological disorders. Overall, the research on NCALD recombinant proteins presents promising avenues for unveiling the complexities of calcium signaling in neurons and its implications for brain health.

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Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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