Analytical Data
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Gene name
MXD3
- Application
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Alternative Names
MXD3;BHLHC13;MAD3;Max dimerization Protein 3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BW11
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Expression Region
1-206aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEPLASN IQVLLQAAEF LERREREAEH GYASLCPHRS PGPIHRRKKR PPQAPGAQDS GRSVHNELEK RRRAQLKRCL ERLKQQMPLG ADCARYTTLS LLRRARMHIQ KLEDQEQRAR QLKERLRSKQ QSLQRQLEQL RGLAGAAERE RLRADSLDSS GLSSERSDSD QEELEVDVES LVFGGEAELL RGFVAGQEHS YSHGGGAWL
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Molecular Weight
26 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MXD3 (Max dimerization protein 3) is a member of the Myc family of transcription factors, which play crucial roles in regulating cellular processes such as growth, differentiation, and apoptosis. Unlike its well-studied counterparts, such as c-Myc, MXD3 functions primarily as a transcriptional repressor, thereby influencing various biological pathways. Research has revealed that MXD3 is involved in cancer biology, as its expression levels can be altered in different tumor types, suggesting a potential role in tumor suppression. Furthermore, MXD3 has been implicated in neurodevelopmental processes, as it is expressed in the nervous system during early development. The study of MXD3 and its recombinant protein is critical for understanding its molecular mechanisms, interactions with other proteins, and its regulatory role in gene expression. Investigating the structural and functional properties of MXD3 can provide insights into its potential as a therapeutic target for cancer and other diseases. Thus, generating and characterizing MXD3 recombinant protein enables researchers to explore its biological functions further and assess its impact on cell behavior, ultimately contributing to the development of targeted therapies.
