Analytical Data
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Gene name
ITGaE
- Application
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Alternative Names
ITGaE；Integrin alpha-E
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P38570
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Expression Region
57-171aa
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AA Sequence
SPRTKRTPGPLHRCSLVQDEILCHPVEHVPIPKGRHRGVTVVRSHHGVLI CIQVLVRRPHSLSSELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDT GDCYSNKEGGGEDDV
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Molecular Weight
38 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ITGaE, or Integrin Alpha E, plays a crucial role in cell adhesion and migration processes, which are fundamental to various biological and pathological events, including immune responses and tumor progression. Research on ITGaE has garnered attention due to its involvement in the behavior of immune cells, particularly in the differentiation and function of T cells and dendritic cells. It is expressed predominantly in tissues where epithelial-immune cell interactions occur, indicating its significance in maintaining tissue integrity and immune regulation. The potential therapeutic implications of targeting ITGaE in diseases like cancer and autoimmune disorders have driven extensive studies into its structure and function. Understanding the molecular mechanisms through which ITGaE operates not only enhances our knowledge of cell signaling and interaction but also opens avenues for novel treatment strategies aimed at modulating immune responses. The development of recombinant ITGaE proteins has facilitated the exploration of its biophysical properties and functional aspects, providing valuable insights into its role in health and disease. As research continues to evolve, ITGaE stands out as a promising candidate for further investigation in both basic and applied biomedical research.
