Analytical Data
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基因名
MAPKSP1
- Application
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别名
LAMTOR3;MAP2K1IP1;MAPKSP1;Ragulator complex Protein LAMTOR3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y2Q5
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表达区间
1-125aa
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氨基酸序列
MLRPKALTQV LSQANTGGVQ STLLLNNEGS LLAYSGYGDT DARVTAAIAS NIWAAYDRNG NQAFNEDNLK FILMDCMEGR VAITRVANLL LCMYAKETVG FGMLKAKAQA LVQYLEEPLT QVAAS
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MAPKSP1, or MAPK/ERK kinase (MEK) signaling pathway species 1, has gained significant attention in recent years due to its critical role in the regulation of cellular functions, including proliferation, differentiation, and survival. As a key component of the mitogen-activated protein kinase (MAPK) signaling pathway, MAPKSP1 participates in transmitting extracellular signals to intracellular responses, thereby influencing various biological processes. Dysregulation of MAPK signaling has been linked to numerous diseases, including cancer, cardiovascular disorders, and neurodegenerative diseases, highlighting the importance of understanding its molecular mechanisms. The recombinant expression of MAPKSP1 allows researchers to produce large quantities of the protein for detailed study, facilitating investigations into its structure, function, and interactions with other signaling molecules. This foundational knowledge is crucial for the development of targeted therapies aimed at modulating MAPK pathway activity, which may lead to novel treatment strategies for diseases where MAPK signaling is aberrant. The study of MAPKSP1 thus represents a promising avenue for advancing our understanding of cellular signaling and disease pathology, ultimately contributing to improved clinical outcomes.
