Analytical Data
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基因名
KRT13
- Application
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别名
KRT13；Keratin. type I cytoskeletal 13
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13646
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表达区间
1-458aa
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氨基酸序列
MSLRLQSSSASYGGGFGGGSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGYGGGLGGGYGGGLGGGFGGGFAGGFVDFGACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWHLKQSPASPERDYSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGLRRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLTRVLAEMREQYEAMAERNRRDAEEWFHTKSAELNKEVSTNTAMIQTSKTEITELRRTLQGLEIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKMLLDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRRTSDVRRP
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分子量
57.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT13, or Keratin 13, is a type of intermediate filament protein primarily expressed in the epithelial tissues of the human body, particularly in mucosal surfaces such as the oral cavity and esophagus. As a component of the cytoskeleton, KRT13 plays a crucial role in maintaining cellular integrity and tissue architecture, and it is vital for the protection against mechanical stress and chemical insults. Alterations in KRT13 expression have been associated with various pathological conditions, including keratinization disorders and certain types of cancer, underscoring its potential as a biomarker for disease progression and a target for therapeutic intervention. Recent advances in recombinant protein technology have enabled the production of purified KRT13, facilitating the study of its structure-function relationships and interactions with other cellular components. Characterizing KRT13 at the molecular level can provide insights into its role in maintaining epithelial homeostasis and its involvement in tissue regeneration and repair processes. Additionally, understanding how KRT13 interacts with other keratins and proteins within the cell can enhance our comprehension of its contribution to various diseases. Thus, research on recombinant KRT13 not only extends our knowledge of keratin biology but also opens avenues for developing novel diagnostic and therapeutic strategies.
