Analytical Data
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基因名
KIF6
- Application
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别名
KIF6; C6orf102Kinesin-like protein KIF6
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6ZMV9
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表达区间
1-293aa
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氨基酸序列
MREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALGESINEARSKIGHLKEEITQRHIQQVALGISENMAVPLMPDQQEEKLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAEEATNLQVNSPAVNSLDHTKPFLQTSDSQHERSQLLSNKSSGGWEVQDQGTGRFDVCDVNARKILPSPCPSPHSQKQSSTSTPLEDSIPKRPVSSIPLTGDSQTDSDIIAFIKARQSILQKQYLQLLCSLFPKSAVSSAQASTNRKGLSDVLVTR
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分子量
59.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KIF6, or kinesin-like protein 6, is a member of the kinesin family of motor proteins, which are essential for intracellular transport. Research on KIF6 has gained attention due to its potential role in various diseases, particularly cardiovascular conditions. Studies have suggested that genetic variations in the KIF6 gene may influence individual responses to certain medications, such as statins, which are commonly prescribed to manage cholesterol levels and reduce the risk of heart disease. The exploration of KIF6 as a therapeutic target is driven by its involvement in key biological processes, including cell motility and organelle transport. Furthermore, the examination of KIF6 protein recombinants has enabled researchers to better understand its function and interactions within the cells. By utilizing advanced techniques such as recombinant DNA technology, scientists have been able to produce and analyze KIF6 protein, offering insights into its structure and mechanisms of action. This research is crucial for unraveling the complexities of KIF6's role in health and disease, potentially leading to more effective personalized medicine approaches. Overall, the ongoing investigation into KIF6 not only sheds light on its biological significance but also holds promise for the development of novel therapeutic strategies in the context of cardiovascular and other related diseases.
