Analytical Data
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Gene name
KIAA1285
- Application
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Alternative Names
ZNF777. KIAA1285
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9ULD5
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Expression Region
1-518aa
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AA Sequence
MRGNYESLVSMDYAISKPDLMSQMERGERPTMQEQEDSEEGETPTDPSAAHDGIVIKIEVQTNDEGSESLETPEPLMGQVEEHGFQDSELGDPCGEQPDLDMQEPENTLEESTEGSSEFSELKQMLVQQRNCTEGIVIKTEEQDEEEEEEEEDELPQHLQSLGQLSGRYEASMYQTPLPGEMSPEGEESPPPLQLGNPTVKRLAPSVHGERHLSENRGASSQQQRNRRGERPFTCMECGKSFRLKINLIIHQRNHIKEGPYECAECEISFRHKQQLTLHQRIHRVRGGCVSPERGPTFNPKHALKPRPKSPSSGSGGGGPKPYKCPECDSSFSHKSSLTKHQITHTGERPYTCPECKKSFRLHISLVIHQRVHAGKHEVSFICSLCGKSFSRPSHLLRHQRTHTGERPFKCPECEKSFSEKSKLTNHCRVHSRERPHACPECGKSFIRKHHLLEHRRIHTGERPYHCAECGKRFTQKHHLLEHQRAHTGERPYPCTHCAKCFRYKQSLKYHLRTHTGE
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Molecular Weight
85.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
KIAA1285, also known as DCTN5 (Dynactin Subunit 5), is a gene that has garnered interest in the field of molecular biology due to its potential role in cellular processes such as mitosis, intracellular transport, and neurodevelopment. Emerging evidence suggests that KIAA1285 is involved in the dynamics of microtubule organization and anchoring, crucial for proper cell division and neuronal function. Studies have shown that mutations or dysregulation of KIAA1285 can lead to various neurodegenerative diseases and developmental disorders. Furthermore, it has been implicated in cancer biology, where alterations in its expression may affect tumor cell behavior and metastasis. Recent advancements in recombinant protein technology have enabled researchers to produce KIAA1285 in vitro, facilitating detailed characterization of its structural and functional properties. By studying the recombinant KIAA1285 protein, scientists aim to elucidate its functional mechanisms, interaction partners, and its overarching role in cellular physiology, potentially paving the way for novel therapeutic targets in diseases associated with KIAA1285 dysregulation. This research not only enhances our understanding of KIAA1285 but also contributes to the broader comprehension of microtubule dynamics and their implications in health and disease.
