Analytical Data
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基因名
KDELC1
- Application
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别名
POGLUT2; EP58; KDELC1; UNQ1910/PRO4357; Protein O-glucosyltransferase 2; EC 2.4.1.-; Endoplasmic reticulum resident protein 58; ER protein 58; ERp58
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UW63
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表达区间
1-502aa
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氨基酸序列
MFGTLLLYCFFLATVPALAETGGERQLSPEKSEIWGPGLKADVVLPARYFYIQAVDTSGNKFTSSPGEKVFQVKVSAPEEQFTRVGVQVLDRKDGSFIVRYRMYASYKNLKVEVKFQGQHVAKSPYILKGPVYHENCDCPLQDSAAWLREMNCPETIAQIQRDLAHFPAVDPEKIAVEIPKRFGQRQSLCHYTLKDNKVYIKTHGEHVGFRIFMDAILLSLTRKVKMPDVELFVNLGDWPLEKKKSNSNIHPIFSWCGSTDSKDIVMPTYDLTDSVLETMGRVSLDMMSVQANTGPPWESKNSTAVWRGRDSRKERLELVKLSRKHPELIDAAFTNFFFFKHDENLYGPIVKHISFFDFFKHKYQINIDGTVAAYRLPYLLVGDSVVLKQDSIYYEHFYNELQPWKHYIPVKSNLSDLLEKLKWAKDHDEEAKKIAKAGQEFARNNLMGDDIFCYYFKLFQEYANLQVSEPQIREGMKRVEPQTEDDLFPCTCHRKKTKDEL
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分子量
84.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KDELC1, a member of the KDEL (Lys-Asp-Glu-Leu) receptor family, plays a crucial role in intracellular trafficking and protein localization. Recent studies have highlighted its involvement in cellular processes such as endoplasmic reticulum (ER) stress response and autophagy, which are essential for maintaining cellular homeostasis. The protein exhibits specific expression patterns in various tissues, indicating a potential role in developmental processes and cellular differentiation. Moreover, emerging evidence suggests that KDELC1 may be implicated in various disease states, including cancer, where its expression is often dysregulated. This has prompted a growing interest in the functional characterization of KDELC1 through recombinant protein studies. By producing and analyzing KDELC1 in a controlled environment, researchers aim to elucidate its mechanisms of action, interaction with other cellular components, and potential as a therapeutic target. Through techniques such as structural biology, binding assays, and functional assays, the investigation of KDELC1 is expected to provide valuable insights into its biological significance and contribute to the understanding of its role in health and disease.
