Analytical Data
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Gene name
TSPAN1
- Application
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Alternative Names
TSPAN1；Tetraspanin-1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O60635
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Expression Region
110-211aa
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AA Sequence
YTTMAEHFLT LLVVPAIKKD YGSQEDFTQV WNTTMKGLKC CGFTNYTDFE DSPYFKENSA FPPFCCNDNV TNTANETCTK QKAHDQKVEG CFNQLLYDIR TN
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Molecular Weight
38 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TSPAN1, a member of the tetraspanin family, is a membrane protein known to play a pivotal role in various cellular processes, including cell proliferation, adhesion, and migration. Research has increasingly focused on TSPAN1 due to its involvement in several physiological and pathological conditions, including cancer progression, where it appears to influence tumor microenvironment interactions and metastatic potential. The protein is thought to act as a molecular organizer, facilitating the formation of specific membrane domains that enhance signaling pathways essential for cell communication. Additionally, studies have suggested that TSPAN1 may serve as a potential biomarker for certain cancers, providing insight into tumor dynamics and patient prognosis. Given its significant role in cell biology and disease, there is a growing interest in characterizing TSPAN1 through recombinant protein techniques. Producing TSPAN1 as a recombinant protein allows for detailed investigation of its structure-function relationships, interactions with other proteins, and potential therapeutic applications. This research not only aims to elucidate the biological mechanisms underlying TSPAN1's function but also explores its utility in developing targeted therapies and diagnostics in oncology. The ongoing studies on TSPAN1 highlight its promise as a focal point for advancing our understanding of key cellular processes and its potential impact on cancer treatments.
