Analytical Data
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基因名
ICAM2
- Application
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别名
ICAM2;Intercellular adhesion molecule 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13598
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表达区间
1-223aa
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氨基酸序列
MSSFGYRTLT VALFTLICCP GSDEKVFEVH VRPKKLAVEP KGSLEVNCST TCNQPEVGGL ETSLDKILLD EQAQWKHYLV SNISHDTVLQ CHFTCSGKQE SMNSNVSVYQ PPRQVILTLQ PTLVAVGKSF TIECRVPTVE PLDSLTLFLF RGNETLHYET FGKAAPAPQE ATATFNSTAD REDGHRNFSC LAVLDLMSRG GNIFHKHSAP KMLEIYEPVS DSQ
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分子量
50 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ICAM-2 (Intercellular Adhesion Molecule-2) is a pivotal glycoprotein that plays a crucial role in the immune response by facilitating the adhesion of leukocytes to endothelial cells, thereby influencing inflammation and immune regulation. It belongs to the immunoglobulin superfamily and is primarily expressed on endothelial cells, where it interacts with lymphocyte function-associated antigen-1 (LFA-1), a vital receptor on T cells, facilitating their migration to sites of inflammation. Research on recombinant ICAM-2 proteins has gained significance in understanding the molecular mechanisms underlying immune cell trafficking and the pathogenesis of various inflammatory diseases. Moreover, studies involving the recombinant expression of ICAM-2 have shown potential applications in immunotherapy, where it could enhance the efficacy of vaccines or serve as a biomarker for certain diseases. With advances in molecular biology techniques, the ability to produce and characterize ICAM-2 as a recombinant protein has opened new avenues for therapeutic interventions, providing insights into its structure-function relationships and potential therapeutic roles in modulating immune responses. The ongoing research into ICAM-2 is not only essential for unraveling its biological functions but also for developing innovative strategies to target and treat inflammatory conditions and associated disorders.












