Analytical Data
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Gene name
NTF3
- Application
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Alternative Names
NTF3；Neurotrophin-3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P20783
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Expression Region
139-257aa
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AA Sequence
YAEHKSHRGEYSVCDSESLWVTDKSSAIDIRGHQVTVLGEIKTGNSPVKQYFYETRCKEARPVKNGCRGIDDKHWNSQCKTSQTYVRALTSENNKLVGWRWIRIDTSCVCALSRKIGRT
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Molecular Weight
17.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
NTF3, or neurotrophin-3, is a member of the neurotrophin family, which plays a crucial role in the development, survival, and function of neurons in the nervous system. Its biological activities are mediated through specific receptors, primarily trkC, which is involved in various neuroprotective and neuroregenerative processes. Research into NTF3 has gained momentum due to its potential therapeutic applications in neurodegenerative diseases, peripheral nerve injuries, and conditions characterized by neuronal loss and dysfunction. The reconstitution of NTF3 as a recombinant protein allows for detailed studies of its structure-function relationship and mechanisms of action. It also facilitates the exploration of its efficacy in promoting neuronal survival and growth in experimental models, with promising implications for therapeutic interventions. Additionally, understanding the pathways regulated by NTF3 can lead to the development of targeted treatments that enhance neuroplasticity and recovery in damaged neural tissues. Recent advancements in protein expression and purification techniques have further invigorated NTF3 research, enabling scientists to produce biologically active forms of the protein for in vitro and in vivo studies. These efforts aim to unlock the full therapeutic potential of NTF3 in regenerative medicine and offer hope for improved outcomes in neurological disorders.
