Analytical Data
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Gene name
IFIT5
- Application
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Alternative Names
FLJ53857; FLJ92678; IFIT-5; IFIT5; IFIT5_HUMAN; Interferon induced protein with tetratricopeptide repeats 5; Interferon-induced protein with tetratricopeptide repeats 5; Retinoic acid and interferon inducible 58 kDa protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13325
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Expression Region
1-482aa
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AA Sequence
MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQLEFLTTKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLSI
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Molecular Weight
78.76 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IFIT5 (Interferon-Inducible Protein 5) is a member of the IFIT protein family, which plays a crucial role in the immune response to viral infections. It is primarily expressed in response to interferons, signaling molecules that are part of the body's early defense mechanism against viral pathogens. Research has shown that IFIT5 is involved in regulating various cellular processes, including antiviral responses and apoptosis. The protein functions by binding to viral RNA, which can inhibit viral replication, thereby contributing to the host's antiviral defense. Additionally, IFIT5 has been implicated in the modulation of cell proliferation and differentiation, indicating its potential role in cancer biology and autoimmune diseases. As a result, studying IFIT5 and other members of the IFIT family is critical for understanding host-pathogen interactions, developing antiviral therapies, and exploring their implications in human health and disease. Recent advancements in molecular biology techniques have enabled researchers to explore the structural and functional characteristics of IFIT5, leading to potential therapeutic applications, including the design of novel antiviral agents and targeted cancer therapies. Overall, the study of IFIT5 and its recombinant protein forms contributes valuable insights into the intricate mechanisms of the immune response and holds promise for innovative medical interventions.
