Analytical Data
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Gene name
IFIT2
- Application
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Alternative Names
CIG-42; cig42; G10P2; GARG 39 ; Glucocorticoid attenuated response gene 39; IFI 54 ; IFI 54K ; IFI-54K; IFI54 ; IFIT 2; IFIT-2; IFIT2; IFIT2_HUMAN; Interferon induced 54 kDa protein ; Interferon induced protein 54 ; Interferon induced protein with tetratricopeptide repeats 2; Interferon. alpha inducible protein (MW 54kD)
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P09913
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Expression Region
1-484aa
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AA Sequence
MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRTEFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVRHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRENGMYGKRKLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEEAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGLESGSLIPSASSWNGEWRIEMWCPLGYC
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Molecular Weight
82.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IFIT2 (Interferon-Inducible Protein 2) is a member of the interferon-stimulated gene (ISG) family, which plays a crucial role in the innate immune response against viral infections. Research shows that IFIT2 is upregulated upon interferon treatment, indicating its involvement in antiviral defense mechanisms. It is particularly known for its capacity to recognize and bind to viral RNA, which aids in inhibiting viral replication and modulating immune responses. Recent studies highlight its potential roles in regulating various cellular processes, including apoptosis, cell cycle, and inflammation, which further positions IFIT2 as a significant player in both antiviral immunity and broader physiological contexts. The recombinant expression of IFIT2 allows researchers to investigate its functional mechanisms and interactions with other proteins, paving the way for potential therapeutic applications in treating viral diseases and modulating immune responses. Understanding the structure and function of IFIT2 at a molecular level could provide insights into developing novel antiviral strategies and enhancing immune system responses against a range of pathogens. As such, the exploration of IFIT2 not only contributes to the fundamental knowledge of host-pathogen interactions but also opens avenues for innovative therapeutic developments in infectious disease management.
