Cat: PA2000-119DB

Recombinant Human CD15 Protein,His

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Analytical Data

  • 基因名

    CD15

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    CD15;CD83 antigen

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q01151

  • 表达区间

    1-205aa

  • 氨基酸序列

    MSRGLQLLLLSCAYSLAPATPEVKVACSEDVDLPCTAPWDPQVPYTVSWVKLLEGGEERMETPQEDHLRGQHYHQKGQNGSFDAPNERPYSLKIRNTTSCNSGTYRCTLQDPDGQRNLSGKVILRVTGCPAQRKEETFKKYRAEIVLLLALVIFYLTLIIFTCKFARLQSIFPDFSKAGMERAFLPVTSPNKHLGLVTPHKTELV

  • 分子量

    23 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

CD15, also known as Lewis X, is a carbohydrate antigen expressed on the surface of human cells, particularly prominent in granulocytes and some tissues of the immune system. It plays a crucial role in various biological processes, including cell adhesion, migration, and immune response modulation. Research on CD15 has gained significant attention due to its involvement in inflammatory responses and its potential role in cancer biology, where it may affect tumor cell behavior and metastasis. The presentation of CD15 on leukocytes has made it a valuable marker in the diagnosis and monitoring of certain hematological malignancies, including acute myeloid leukemia and chronic lymphocytic leukemia. The development of recombinant CD15 proteins has opened new avenues for understanding its functional mechanisms and interactions in vitro and in vivo, paving the way for therapeutic applications. By generating specific antibodies against CD15, researchers hope to harness the protein’s properties for targeted therapies, immunotherapeutics, and diagnostic tools. Investigating the structure-function relationship of recombinant CD15 proteins will also enhance our understanding of its role in immune evasion and establish a foundation for innovative strategies in the treatment of cancer and inflammatory diseases. Overall, the study of CD15 and its recombinant forms holds promise for advancing our knowledge of immunology and oncology, potentially leading to improved clinical outcomes for patients.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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