Analytical Data
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Gene name
Mindy2
- Application
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Alternative Names
Mindy2；FAM63B；KIAA1164；Ubiquitin carboxyl-terminal hydrolase MINDY-2
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Species
Mouse
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6PDI6
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Expression Region
1-601aa
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AA Sequence
MENSPDSPQPLELGVAAGRVSPPEGRRRGGREAEDGPAGRAVDSGGQGAAAAAARSSLGDPTSPSQLGCGAGSDLKDGASSSPAASEVPSRGQHKVTASPELAEAAAGRGSGPVGDTGTCRVEQAAEEPSSTGAPSSSCSEPSPPGDSPSLDSLESFSNLHSFPSSSEFNSEEGAETRVPEDVEEGAAGPPRAAPLCKEEEEDPAQVLAASKERFPGQSVYHIKWIQWKEENTPIITQNENGPCPLLAILNVLLLAWKVKLPPMMEIITAEQLMEYLGDYMLEAKPKEISEIQRVNYEQNMSDAMAILHKLQTGLDVNVRFTGVRVFEYTPECIVFDLLDIPLYHGWLVDPQIDDIVKAVGNCSYNQLVEKIISCKQSDNSQLVSEGFVAEQFLNNTATQLTYHGLCELTSTVQEGELCVFFRNNHFSTMTKYKGQLYLLVTDQGFLTEEKIVWESLHNVDGDGNFCDSEFHLRPPSDPETVYKGQQDQIDQDYLMALSLQQEQQSQEINWEQIPEGISDLELAKKLQEEEDRRASQYYQEQEQAQAVVTTTTPSTQAQQGQPAQASPSSIKQPGNSERKRKEPREKDKEKEKEKNSCVIL
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Molecular Weight
93.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Mindy2, also known as Mindy-2 or MINDY2, is a member of the MINDY family of proteins, which are implicated in various cellular processes, including endosomal sorting and membrane trafficking. The study of Mindy2 has garnered attention due to its potential role in neurodevelopment and cancer biology. Research indicates that Mindy2 may be involved in the regulation of autophagy and the endosomal-lysosomal pathway, critical for cellular homeostasis. Dysregulation of these processes can lead to an array of diseases, highlighting the importance of understanding the functional mechanisms of Mindy2. Recent studies have suggested that Mindy2 may interact with specific proteins and signaling pathways, thereby influencing key processes such as cell proliferation and differentiation. As scientists continue to explore the molecular functions of Mindy2, the protein emerges as a promising target for therapeutic intervention in disorders linked to cellular trafficking abnormalities, including neurodegenerative diseases and cancers. Further investigation into its structure and interactions is necessary to elucidate its precise biological roles and potential implications in health and disease.
