Analytical Data
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Gene name
Defb19
- Application
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Alternative Names
Defb19；DEFB120；DEFB19；DEFB20；Beta-defensin 119
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N690
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Expression Region
22-84aa
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AA Sequence
KRHILRCMG NSGICRASCK KNEQPYLYCR NCQSCCLQSY MRISISGKEE NTDWSYEKQW PRLP
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Molecular Weight
9.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Defb19, a member of the defensin family, is an important antimicrobial peptide found in various species, including humans and mice. It plays a crucial role in the innate immune response by providing a first line of defense against a wide range of pathogens, including bacteria, fungi, and viruses. Research into Defb19 has gained momentum due to its potential therapeutic applications, particularly in the face of increasing antibiotic resistance. Studies have shown that Defb19 exhibits strong antimicrobial activity and can modulate immune responses, making it a candidate for developing novel antimicrobial agents or immune modulators. Additionally, understanding the molecular mechanisms underlying Defb19's action can shed light on the broader field of host-pathogen interactions and innate immunity. As research progresses, the characterization of Defb19 in terms of its structure, function, and regulation is essential for elucidating its role in health and disease, paving the way for innovative treatments and preventive strategies against infectious diseases.
