Analytical Data
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基因名
G3BP1
- Application
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别名
G3BP1；G3BP;Ras GTPase-activating Protein-binding Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q13283
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表达区间
1-466aa
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氨基酸序列
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDSNGK PADAVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSN NNQALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVFGGFVTEPQEESE EEVEEPEERQQTPEVVPDDSGTFYDQAVVSNDMEEHLEEPVAEPEPDPEP EPEQEPVSEIQEEKPEPVLEETAPEDAQKSSSPAPADIAQTVQEDLRTFS WASVTSKNLPPSGAVPVTGIPPHVVKVPASQPRPESKPESQIPPQRPQRD QRVREQRINIPPQRGPRPIREAGEQGDIEPRRMVRHPDSHQLFIGNLPHE VDKSELKDFFQSYGNVVELRINSGGKLPNFGFVVFDDSEPVQKVLSNRPI MFRGEVRLNVEEKKTRAAREGDRRDNRLRGPGGPRGGLGGGMRGPPRGGM VQKPGFGVGRGLAPRQVEHHHHHH
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分子量
53 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
G3BP1 (GTPase-activating protein 1) is a crucial protein involved in the regulation of stress granule formation, apoptosis, and cellular response to stress. Its role in various cellular processes has garnered significant interest in the fields of molecular biology and biochemistry. Research has shown that G3BP1 participates in the innate immune response, interacting with viral proteins and influencing the host's ability to combat infections. Given its involvement in several pathophysiological conditions, including neurodegenerative diseases and cancer, G3BP1 has emerged as a potential therapeutic target. The recombinant expression of G3BP1 allows for the detailed study of its structure and function, enabling researchers to dissect its molecular mechanisms and interactions. Furthermore, producing G3BP1 as a recombinant protein facilitates various assays, including binding studies and structural analysis, contributing to a deeper understanding of its role in cellular processes. As the field progresses, exploring G3BP1's function through recombinant protein research may reveal novel insights into its potential as a biomarker for disease or a target for drug development.
