Analytical Data
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基因名
MYO5A
- Application
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别名
MYO5A;MYH12;Unconventional myosin-Va
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y4I1
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MYO5A, or myosin 5A, is a motor protein that plays a crucial role in cellular transport and organization, particularly in the movement of organelles and the maintenance of cellular architecture. It belongs to the myosin superfamily, which is characterized by its capacity to interact with actin filaments, facilitating a range of motility functions in eukaryotic cells. Abnormalities in MYO5A have been linked to various human disorders, including Griscelli syndrome, a rare genetic condition that affects pigmentation and immune responses. Research into MYO5A recombinant protein has gained significance due to its potential applications in understanding the underlying mechanisms of these diseases and its utility in biotechnology and therapeutic development. The recombinant form of MYO5A allows scientists to investigate its structure-function relationships, elucidate its role in intracellular transport, and assess how mutations contribute to pathological conditions. Moreover, recombinant MYO5A can be utilized in high-throughput screening assays for drug discovery, particularly for compounds that may modulate its interactions with actin or other cellular partners. Overall, the study of MYO5A recombinant protein not only enhances our understanding of fundamental cellular processes but also opens avenues for novel therapeutic strategies targeting motor protein-related diseases.












