Analytical Data
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基因名
KRT40
- Application
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别名
KRT40；KA36；Keratin. type I cytoskeletal 40
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6A162
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表达区间
1-431aa
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氨基酸序列
MTSDCSSTHC SPESCGTASG CAPASSCSVE TACLPGTCAT SRCQTPSFLS RSRGLTGCLL PCYFTGSCNS PCLVGNCAWC EDGVFTSNEK ETMQFLNDRL ASYLEKVRSL EETNAELESR IQEQCEQDIP MVCPDYQRYF NTIEDLQQKI LCTKAENSRL AVQLDNCKLA TDDFKSKYES ELSLRQLLEA DISSLHGILE ELTLCKSDLE AHVESLKEDL LCLKKNHEEE VNLLREQLGD RLSVELDTAP TLDLNRVLDE MRCQCETVLA NNRREAEEWL AVQTEELNQQ QLSSAEQLQG CQMEILELKR TASALEIELQ AQQSLTESLE CTVAETEAQY SSQLAQIQCL IDNLENQLAE IRCDLERQNQ EYQVLLDVKA RLEGEINTYW GLLDSEDSRL SCSPCSTTCT SSNTCEPCSA YVICTVENCC L
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分子量
48.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
KRT40, or Keratin 40, is a type II keratin that plays a critical role in the structural integrity and function of epithelial cells. As an essential component of the cytoskeleton in various tissues, KRT40 has been implicated in several cellular processes, including cell differentiation, proliferation, and apoptosis. Research into KRT40 has gained momentum due to its potential involvement in skin disorders and its expression patterns in certain cancers, where abnormal keratin expression may serve as a biomarker or therapeutic target. The study of recombinant KRT40 protein is particularly important for understanding its biological functions and interactions at the molecular level. By producing and characterizing KRT40 as a recombinant protein, researchers can evaluate its role in maintaining cell structure and integrity, as well as elucidate its impact on cell signaling pathways. Furthermore, recombinant KRT40 can be used in functional assays, drug screening, and studies aimed at developing targeted therapies for related skin diseases and tumors. Overall, the exploration of KRT40 through recombinant protein research not only deepens our understanding of keratin biology but also opens new avenues for clinical applications in regenerative medicine and cancer treatment.
