Cat: PA1000-9731

Recombinant Human KRT33A Protein,His

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Analytical Data

  • Gene name

    KRT33A

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    KRT33A;HHA3-I;HKA3A;KRTHA3A;Keratin. type I cuticular Ha3-I

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    O76009

  • Expression Region

    1-404aa

  • AA Sequence

    MSYSCGLPSL SCRTSCSSRP CVPPSCHGCT LPGACNIPAN VSNCNWFCEG SFNGSEKETM QFLNDRLASY LEKVRQLERD NAELENLIRE RSQQQEPLVC ASYQSYFKTI EELQQKILCS KSENARLVVQ IDNAKLASDD FRTKYETELS LRQLVESDIN GLRRILDELT LCRSDLEAQV ESLKEELLCL KQNHEQEVNT LRCQLGDRLN VEVDAAPTVD LNQVLNETRS QYEALVETNR REVEQWFATQ TEELNKQVVS SSEQLQSYQA EIIELRRTVN ALEIELQAQH NLRDSLENTL TESEARYSSQ LSQVQRLITN VESQLAEIRS DLERQNQEYQ VLLDVRARLE CEINTYRSLL ESEDCKLPSN PCATTNACDK STGPCISNPC GLRARCGPCN TFGY

  • Molecular Weight

    45.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

KRT33A, a type of cytokeratin protein, belongs to the keratin family, which plays a crucial role in the structural integrity and function of epithelial tissues. Research into KRT33A has gained attention due to its potential involvement in various biological processes and diseases, particularly in skin disorders and epithelial tumors. Cytokeratins, including KRT33A, are essential for maintaining the mechanical stability of cells and tissues, and aberrations in their expression can be indicative of pathological conditions. Notably, KRT33A is expressed during certain stages of epithelial cell differentiation, suggesting its significance in developmental biology. Its association with disease mechanisms underscores the importance of studying KRT33A not only for understanding the fundamental aspects of cell biology but also for identifying novel therapeutic targets. Recent advances in proteomics and genomics have facilitated the exploration of KRT33A's role in cancer progression and metastasis, highlighting its potential as a biomarker for prognosis and treatment response. Overall, ongoing research into KRT33A aims to unravel its functions and clinical implications, paving the way for innovative approaches in diagnosing and treating epithelial-related diseases.

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