Analytical Data
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Gene name
GPR87
- Application
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Alternative Names
G-protein coupled receptor 95
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BY21
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Expression Region
1-358aa
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AA Sequence
MGFNLTLAKLPNNELHGQESHNSGNRSDGPGKNTTLHNEFDTIVLPVLYLIIFVASILLNGLAVWIFFHIRNKTSFIFYLKNIVVADLIMTLTFPFRIVHDAGFGPWYFKFILCRYTSVLFYANMYTSIVFLGLISIDRYLKVVKPFGDSRMYSITFTKVLSVCVWVIMAVLSLPNIILTNGQPTEDNIHDCSKLKSPLGVKWHTAVTYVNSCLFVAVLVILIGCYIAISRYIHKSSRQFISQSSRKRKHNQSIRVVVAVFFTCFLPYHLCRIPFTFSHLDRLLDESAQKILYYCKEITLFLSACNVCLDPIIYFFMCRSFSRRLFKKSNIRTRSESIRSLQSVRRSEVRIYYDYTDV
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Molecular Weight
44.5 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GPR87, a member of the G protein-coupled receptor (GPCR) family, has gained interest in recent years due to its potential implications in various physiological and pathological processes. Initially classified as an orphan receptor, GPR87's endogenous ligands and biological functions have gradually been elucidated, revealing its involvement in the regulation of cell proliferation, apoptosis, and migration. Elevated expression levels of GPR87 have been associated with several types of cancers, including lung and breast cancer, suggesting its role in tumor progression and metastasis. Its activation is believed to influence key signaling pathways such as those involving phospholipase C and ERK, highlighting its potential as a therapeutic target. Moreover, GPR87 has been implicated in neurodegenerative disorders, further broadening its relevance in health and disease. Research on GPR87 recombinant proteins enables the exploration of its structure-function relationships and interaction with various ligands, which is crucial for drug development. Understanding the mechanistic pathways mediated by GPR87 not only enhances our knowledge of GPCR biology but also paves the way for innovative therapeutic approaches in cancer treatment and neurobiology. As such, the study of GPR87 recombinant protein reflects a significant advancement in GPCR research, emphasizing the importance of unraveling the complexities of receptor signaling in order to devise more effective medical interventions.
