Analytical Data
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基因名
LAMP5
- Application
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别名
LAMP5；C20orf103；Lysosome-associated membrane glycoProtein 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UJQ1
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表达区间
1-280aa
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氨基酸序列
MDLQGRGVPSIDRLRVLLMLFHTMAQIMAEQEVENLSGLSTNPEKDIFVVRENGTTCLMAEFAAKFIVPYDVWASNYVDLITEQADIALTRGAEVKGRCGHSQSELQVFWVDRAYALKMLFVKESHNMSKGPEATWRLSKVQFVYDSSEKTHFKDAVSAGKHTANSHHLSALVTPAGKSYECQAQQTISLASSDPQKTVTMILSAVHIQPFDIISDFVFSEEHKCPVDEREQLEETLPLILGLILGLVIMVTLAIYHVHHKMTANQVQIPRDRSQYKHMG
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分子量
31.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
LAMP5 (Lysosomal Associated Membrane Protein 5) is an integral membrane protein predominantly expressed in the brain and is a member of the LAMP family, which plays a crucial role in lysosomal function and cellular homeostasis. The study of LAMP5 is particularly significant in the context of neurodegenerative diseases, where lysosomal dysfunction is increasingly recognized as a contributing factor. Research has indicated that LAMP5 may be involved in autophagy and the degradation of neurotoxic proteins, making it a potential target for therapeutic interventions. Additionally, LAMP5 expression has been linked to synaptic activity and plasticity, suggesting its possible involvement in cognitive functions and neurodevelopmental processes. The development and characterization of recombinant LAMP5 proteins have enabled scientists to explore its structure-function relationships, interaction partners, and regulations in various biological contexts. By investigating the molecular mechanisms underlying LAMP5's role in health and disease, researchers aim to uncover novel insights that could lead to innovative strategies for treating neurological disorders, ultimately enhancing our understanding of lysosomal biology and its implications for brain health.
