Analytical Data
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Gene name
GOLGA1
- Application
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Alternative Names
Gap junction protein alpha 4 37kD; GOGA1_HUMAN; Golga 1; GOLGA1; Golgi autoantigen golgin subfamily a 1; Golgi autoantigen golgin subfamily A member 1 ; Golgi autoantigen golgin subfamily a1.; Golgin A1; Golgin subfamily A member 1; Golgin-97; Golgin97 ; MGC33154
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92805
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Expression Region
1-767aa
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AA Sequence
MFAKLKKKIAEETAVAQRPGGATRIPRSVSKESVASMGADSGDDFASDGSSSREDLSSQLLRRNEQIRKLEARLSDYAEQVRNLQKIKEKLEIALEKHQDSSMRKFQEQNETFQANRAKMAEGLALALARKDQEWSEKMDQLEKEKNILTAQLQEMKNQSMNLFQRRDEMDELEGFQQQELSKIKHMLLKKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGIVAAQETQIQELAAANQESSHVQQQALALEQQFLERTQALEAQIVALERMRAADQTTAEQGMRQLEQENAALKECRNEYERSLQNHQFELKKLKEEWSQREIVSVAMAQALEEVRKQREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELEALRTLKAEEAAVVAEQEDLLRLRGPLQAEALSVNESHVTSRAMQDPVFQLPTAGRTPNGEVGAMDLTQLQKEKQDLEQQLLEKNKTIKQMQQRMLELRKTLQKELKIRPDNELFEVREKPGPEMANMAPSVTNNTDLTDAREINFEYLKHVVLKFMSCRESEAFHLIKAVSVLLNFSQEEENMLKETLEYKMSWFGSKPAPKGSIRPSISNPRIPWS
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Molecular Weight
114.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
GOLGA1, also known as Golgin A1, is a member of the golgin family of proteins, which are localized in the Golgi apparatus and play critical roles in maintaining its structure and function. Research into GOLGA1 has gained attention due to its involvement in several cellular processes, including Golgi organization, vesicular trafficking, and protein sorting. Disruption or abnormal expression of GOLGA1 has been linked to various diseases, including cancer, where altered Golgi function can affect cellular signaling and proliferation. Additionally, GOLGA1 is becoming a point of interest in studies related to neurodegenerative disorders and viral infections, as its activity is often hijacked by pathogens to aid in their replication and spread. Recent advances in molecular biology techniques have enabled the exploration of GOLGA1's structure-function relationships, paving the way for potential therapeutic strategies that target Golgi-related dysfunctions. Thus, the recombinant expression of GOLGA1 protein is essential for evaluating its biochemical properties, understanding receptor-ligand interactions, and unraveling its role in disease mechanisms, thereby providing insights into novel intervention strategies in the context of human health and pathology.
