Analytical Data
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Gene name
SULT1E1
- Application
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Alternative Names
SULT1E1；STE;Sulfotransferase 1E1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P49888
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Expression Region
1-294aa
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AA Sequence
MNSELDYYEK FEEVHGILMY KDFVKYWDNV EAFQARPDDL VIATYPKSGT TWVSEIVYMI YKEGDVEKCK EDVIFNRIPF LECRKENLMN GVKQLDEMNS PRIVKTHLPP ELLPASFWEK DCKIIYLCRN AKDVAVSFYY FFLMVAGHPN PGSFPEFVEK FMQGQVPYGS WYKHVKSWWE KGKSPRVLFL FYEDLKEDIR KEVIKLIHFL ERKPSEELVD RIIHHTSFQE MKNNPSTNYT TLPDEIMNQK LSPFMRKGIT GDWKNHFTVA LNEKFDKHYE QQMKESTLKF RTEI
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SULT1E1, or sulfotransferase 1E1, is a key enzyme involved in the sulfonation of various hormones, neurotransmitters, and xenobiotics, playing a crucial role in the metabolism and detoxification processes in the human body. Research on SULT1E1 has gained attention due to its involvement in the regulation of estrogen signaling and its potential implications in hormone-related cancers. The enzyme's activity can influence the bioavailability and efficacy of therapeutic agents, making it relevant in pharmacology and toxicology. Additionally, genetic polymorphisms in the SULT1E1 gene may affect individual responses to drugs and susceptibility to diseases, underscoring the importance of understanding its functional properties. Recombinant SULT1E1 protein production allows for in-depth studies of the enzyme’s catalytic mechanisms, substrate specificity, and inhibitors, facilitating drug development and personalized medicine approaches. Advances in biotechnology have enabled the expression and purification of active recombinant SULT1E1, offering a valuable tool for researchers aiming to elucidate its role in metabolic pathways and potential therapeutic targets. These investigations could lead to enhanced strategies for disease prevention and treatment through a better understanding of SULT1E1’s biological functions and interactions with endogenous and exogenous compounds.
