Analytical Data
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Gene name
SLC44A4
- Application
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Alternative Names
(Solute carrier family 44 member 4)(Thiamine pyrophosphate transporter 1)(hTPPT1)
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Species
Human
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Source
E. coli
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Tag
N- His & C- Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q53GD3
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Expression Region
56-229aa
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Molecular Weight
26.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC44A4, part of the solute carrier family, is a crucial gene encoding a protein primarily expressed in tissues such as the brain and placenta. This protein is thought to play a significant role in the transport of metabolites, particularly in the homeostasis of choline and its derivatives, which are essential for various physiological processes, including cell membrane integrity and neurotransmitter synthesis. Recent studies have linked SLC44A4 to several conditions, such as neurological disorders and fertility issues, underscoring its potential importance in human health. The research surrounding recombinant SLC44A4 protein has garnered interest due to its implications for understanding the molecular mechanisms underlying these conditions and its potential as a therapeutic target. The production of recombinant SLC44A4 protein allows for detailed characterization of its functional properties, interaction with other cellular components, and influence on cellular signaling pathways. Moreover, insights gained from this research could lead to novel strategies for disease intervention and biomarker development, highlighting the significance of SLC44A4 in biomedical research. As the scientific community continues to unravel the complexities of solute carriers, the focus on SLC44A4's role in health and disease is expected to expand, fostering a deeper understanding of its contributions to human biology.
