Analytical Data
-
基因名
DYNLT3
- Application
-
别名
DYNLT3；TCTE1L；TCTE1XL;Dynein light chain Tctex-type 3
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P51808
-
表达区间
1-116aa
-
氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSMEEYHRH CDEVGFNAEE AHNIVKECVD GVLGGEDYNH NNINQWTASI VEQSLTHLVK LGKAYKYIVT CAVVQKSAYG FHTASSCFWD TTSDGTCTVR WENRTMNCIV NVFAIAIVL
-
分子量
16 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
DYNLT3 (Dynein Light Chain 3) is a member of the dynein light chain family, which plays a crucial role in the intracellular transport mechanisms mediated by dynein motor proteins. These proteins are essential for various cellular processes, including organelle positioning, endocytosis, and mitosis. Given the importance of dynein in maintaining cellular homeostasis, alterations in DYNLT3 expression or function can lead to a variety of diseases, particularly neurodegenerative conditions. Recent studies have focused on the reconstitution and characterization of DYNLT3 to better understand its role in dynein complexes and motor function. The recombinant production of DYNLT3 allows researchers to investigate its structural properties, binding interactions, and functional implications in cellular transport. Additionally, studying DYNLT3 in the context of disease can provide insights into potential therapeutic targets aimed at restoring proper cellular transport mechanisms. By leveraging advanced techniques such as cryo-electron microscopy and biophysical assays, researchers are uncovering the intricate networks in which DYNLT3 operates, paving the way for novel interventions in diseases associated with dysfunction in intracellular transport.
