Analytical Data
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Gene name
SERPINE3
- Application
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Species
Human
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Source
E. coli
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Tag
C- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A8MV23
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Expression Region
21-424aa
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Molecular Weight
51.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SERPINE3, also known as Serpin E3, is a member of the serpin (serine protease inhibitor) superfamily that plays a crucial role in various physiological and pathological processes, including tissue remodeling, inflammation, and cell migration. Research into SERPINE3 has garnered interest due to its implications in cancer biology, particularly in the regulation of tumor growth and metastasis. Elevated levels of SERPINE3 have been associated with poor prognosis in several types of cancer, suggesting its potential as a biomarker for disease progression and a therapeutic target. Moreover, SERPINE3 has been implicated in neurodegenerative diseases and cardiovascular conditions, highlighting its diverse biological functions. The recombinant protein form of SERPINE3 facilitates in-depth studies into its structure-function relationships, mechanism of action, and interactions with other proteins. Understanding these dynamics is essential for elucidating the role of SERPINE3 in disease states and developing potential interventions. Advances in protein engineering and expression systems have enabled the efficient production of SERPINE3, paving the way for therapeutic applications and further research into its regulatory mechanisms within various cellular contexts. As such, SERPINE3 remains a focal point for ongoing studies aimed at unraveling its multifaceted roles in health and disease, thereby contributing to the development of novel therapeutic strategies.
