Analytical Data
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基因名
UCN2
- Application
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别名
UCN2；SRP；URP；Urocortin-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96RP3
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表达区间
72-112aa
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氨基酸序列
IVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC
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分子量
17.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
UCN2, or Urocortin 2, is a peptide belonging to the corticotropin-releasing factor (CRF) family, which plays an essential role in the body’s stress response, influencing various physiological processes such as anxiety, appetite, and cardiovascular function. Research has revealed that UCN2 is involved in several pathophysiological conditions, including depression and obesity, making it a potential therapeutic target for related disorders. The recombinant production of UCN2 protein is vital for investigating its molecular mechanisms and biological functions, allowing researchers to elucidate its signaling pathways and interactions with specific receptors, such as CRF receptors 1 and 2. By using recombinant DNA technology, scientists can generate large quantities of UCN2, facilitating in vitro and in vivo studies that could lead to the development of novel therapeutic strategies aimed at modulating UCN2 signaling. Furthermore, understanding how UCN2 interacts with other neuropeptides and systems can provide deeper insights into its role in neuroendocrine regulation and its potential as a biomarker for stress-related conditions. Thus, the study of recombinant UCN2 proteins is not only fundamental for basic science but also holds promise for clinical applications in mental health and metabolic disorders.
