Analytical Data
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Gene name
UCN2
- Application
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Alternative Names
UCN2；SRP；URP；Urocortin-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96RP3
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Expression Region
72-112aa
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AA Sequence
IVLSLDVPIGLLQILLEQARARAAREQATTNARILARVGHC
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Molecular Weight
17.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UCN2, or Urocortin 2, is a peptide belonging to the corticotropin-releasing factor (CRF) family, which plays an essential role in the body’s stress response, influencing various physiological processes such as anxiety, appetite, and cardiovascular function. Research has revealed that UCN2 is involved in several pathophysiological conditions, including depression and obesity, making it a potential therapeutic target for related disorders. The recombinant production of UCN2 protein is vital for investigating its molecular mechanisms and biological functions, allowing researchers to elucidate its signaling pathways and interactions with specific receptors, such as CRF receptors 1 and 2. By using recombinant DNA technology, scientists can generate large quantities of UCN2, facilitating in vitro and in vivo studies that could lead to the development of novel therapeutic strategies aimed at modulating UCN2 signaling. Furthermore, understanding how UCN2 interacts with other neuropeptides and systems can provide deeper insights into its role in neuroendocrine regulation and its potential as a biomarker for stress-related conditions. Thus, the study of recombinant UCN2 proteins is not only fundamental for basic science but also holds promise for clinical applications in mental health and metabolic disorders.
