Analytical Data
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基因名
CPT1B
- Application
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别名
CPT1B;KIAA1670;Carnitine O-palmitoyltransferase 1. muscle isoform
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92523
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表达区间
673-772aa
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氨基酸序列
FLAEVLSEPWRLSTSQIPQSQIRMFDPEQHPNHLGAGGGFGPVADDGYGV SYMIAGENTIFFHISSKFSSSETNAQRFGNHIRKALLDIADLFQVPKAYS
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分子量
37 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CPT1B (Carnitine Palmitoyltransferase 1B) is a crucial enzyme in the mitochondrial fatty acid oxidation pathway, playing a vital role in energy metabolism by facilitating the transport of long-chain fatty acids into the mitochondria. Abnormalities in CPT1B expression and function have been linked to various metabolic disorders, including obesity, insulin resistance, and certain cardiomyopathies. The study of CPT1B recombinant proteins has gained increasing attention in recent years as researchers seek to delineate its physiological roles and regulatory mechanisms. By using recombinant DNA technology, scientists can produce CPT1B in heterologous systems, allowing for detailed analyses of enzyme kinetics, substrate specificity, and potential post-translational modifications. Such studies are essential for understanding the molecular basis of CPT1B-related diseases and may pave the way for developing targeted therapeutic strategies. Furthermore, exploring the interactions of CPT1B with other metabolic pathways may provide insights into its broader effects on cellular energy homeostasis and overall metabolism. Consequently, research on CPT1B recombinant proteins not only enhances our understanding of lipid metabolism but also holds promise for advancing metabolic disease therapeutics.












