Analytical Data
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基因名
SLC16A1
- Application
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别名
SLC16A1；MCT1；Monocarboxylate transporter 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P53985
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表达区间
1-500aa
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氨基酸序列
MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESPV
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分子量
53.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC16A1, also known as the monocarboxylate transporter 1 (MCT1), is a key protein involved in the transport of lactate, pyruvate, and other monocarboxylates across cell membranes. This transporter plays a crucial role in various physiological processes, including energy metabolism, pH regulation, and cellular signaling. Research on SLC16A1 has gained momentum due to its implications in various diseases, such as cancer, where altered monocarboxylate transport can affect tumor growth and metastasis. Furthermore, mutations in the SLC16A1 gene have been associated with neurological disorders, including developmental delays and seizures, highlighting its importance in brain metabolism. Understanding the structure and function of SLC16A1 through the study of recombinant protein can provide insights into its mechanisms of action and regulation. Additionally, exploring the potential of SLC16A1 as a therapeutic target may open new avenues for drug development in conditions associated with metabolic dysregulation. The recombinant expression of SLC16A1 allows researchers to investigate its biophysical properties, substrate specificity, and interaction with pharmacological agents, ultimately contributing to a better understanding of its role in health and disease.
