Analytical Data
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基因名
CHD3
- Application
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别名
CHD3；Chromodomain-helicase-DNA-binding Protein 3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q12873
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
Research on CHD3 (Chromodomain Helicase DNA-binding protein 3), a member of the Chromodomain Helicase DNA-binding family, has gained significant attention due to its crucial role in chromatin remodeling and regulation of gene expression. CHD3 is known to be involved in the assembly and maintenance of repressive chromatin structures, influencing various cellular processes such as differentiation, proliferation, and response to DNA damage. Aberrant expression or mutation of CHD3 has been associated with several diseases, including certain types of cancer and developmental disorders. This has prompted scientists to investigate its molecular mechanisms and functional implications further. Recent studies have employed recombinant protein techniques to produce CHD3 for biochemical assays, allowing for a deeper understanding of its interactions and regulatory functions. The ability to generate and study CHD3 in vitro is pivotal for unraveling its contributions to chromatin dynamics and establishing its potential as a therapeutic target. Given its importance in maintaining genomic stability and regulating transcription, ongoing research into CHD3 is essential for elucidating its role in health and disease.
